Plateforme de biopharmacie – Université de Montréal (animal/human)

Name of entity

Platform of Biopharmacy

Entity type

Plateform/Specialized Services

Keywords

Pharmaceutical formulation
Biopharmaceutical development
Physicochemical characterization
ADME (Absorption, Distribution, Metabolism, Excretion)
DMPK (Drug Metabolism and Pharmacokinetics)
Metabolism
Toxicity / Toxicokinetics
Solubility / Bioavailability
Stability
Drug release

Area of expertise

The Biopharmaceutics Platform of the Faculty of Pharmacy at the Université de Montréal provides research support services to both academic and industrial partners.
This technological infrastructure enables the evaluation of the biopharmaceutical properties of drug candidates during the discovery and preclinical development phases.
The platform’s two main areas of expertise are:
1. Development and characterization of pharmaceutical formulations
2. ADME studies (absorption, distribution, metabolism, and excretion), including in vitro assays and in vivo pharmacokinetic studies

Services offered

Development of pharmaceutical formulations (solutions, suspensions, nanoparticles, liposomes, semi-solid and solid forms)
Solubility, stability, and compatibility studies
Optimization of excipients and bioavailability
Drug release testing and dissolution profiling
ADME studies (absorption, distribution, metabolism, excretion)
In vitro assays (microsomes, hepatocytes, Caco-2 permeability, plasma stability, plasma protein binding, etc.)
Identification and characterization of metabolites (in vitro and in vivo)
In vivo pharmacokinetic studies (rodent and canine models)
Bioanalytical analysis using LC-MS/MS
Physicochemical characterization (pH, logP, particle size, zeta potential, viscosity, etc.)
Scientific support for experimental design and data interpretation

Directeur

Grégoire Leclair
info@pfbio.ca
(514) 343-6111
https://pfbio.ca/

Responsable

Mihaela Friciu (coordinatrice)
info@pfbio.ca
514-343-6111 poste 04140
https://pfbio.ca/

Address

Plateforme de Biopharmacie
Faculté de pharmacie, Université de Montréal
2940 Chemin de la Polytechnique
Montréal (Québec) H3T 1J4