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Reduction of DUSP4 enhances macrophage infiltration and contributes to renal fibrosis
April 17th, 2023
Science Pearls
Chronic kidney disease (CKD) is the leading cause of end-stage kidney disease. Renal interstitial fibrosis (RIF), an essential characteristic of CKD, is associated with renal function decline. Although macrophages are known to play a role in the generation of fibrosis, their contribution to RIF is not well elucidated. Our laboratory has previously demonstrated that the […]
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