News
59th European Association for the Study of Diabetes (EASD) Annual Meeting
October 19th, 2023
Science Pearls
Comparison between two commercial automated insulin delivery (AID) systems (Medtronic 670G/770G as a first-generation AID vs. Tandem Control-IQ as a second-generation AID with auto-correction feature) remains scarce. We conducted this post-hoc analysis of a prospective, observational, real-world study involving 52 adults with T1D (63% females). The findings suggested that compared with the first-generation AID system, the second-generation AID system achieved a higher time in range, mainly due to less time spent in hyperglycemia, among adults with type 1 diabetes in real-world settings. The benefits of less hyperglycemia may be mainly attributed to the auto-correction feature. This is the first study comparing two different brands of commercial AID systems.
Reduction of DUSP4 enhances macrophage infiltration and contributes to renal fibrosis
April 17th, 2023
Science Pearls
Chronic kidney disease (CKD) is the leading cause of end-stage kidney disease. Renal interstitial fibrosis (RIF), an essential characteristic of CKD, is associated with renal function decline. Although macrophages are known to play a role in the generation of fibrosis, their contribution to RIF is not well elucidated. Our laboratory has previously demonstrated that the […]
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The Research Network on cardiometabolic health, diabetes and obesity aims to develop research excellence in these areas, to transmit knowledge and to develop the knowledge to promote the quality of life of Quebecers and Quebecers.